IFI-C · Hydroxycitronellal

Specimen SS-F-CLB-800 // COOL BURN · IFI-C

Hydroxycitronellal V-IV-B

Lavandula angustifolia

Lavender

Tier VHydroxycitronellal

Target Trait

2.88×

fold-change

hydroxycitronellal accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-800

Genomic Edits

7

GC Content

47.4%

Construct Length

4,015 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro T7/SP6 cell-free

Host Strain

Cell-free

Receptor Target

TRPM8

IFI Score

288

Pathway Edits

  • CES1 (citronellol synthase 1) codon-optimized overexpression in Lavandula angustifolia
  • COX1 (citronellol oxidase 1) precision upregulation for hydroxycitronellal formation
  • ADH1 (alcohol dehydrogenase 1) loss-of-function to prevent citronellal reduction back to citronellol
  • GPPS (geranyl pyrophosphate synthase) upregulation for monoterpene precursor maintenance

Key Interventions

Hydroxycitronellal terpene aldehyde overproduction via CES1/COX1 sequential pathway upregulationADH1 suppression to prevent competing citronellal/citronellol equilibriumTRPM8 activation with distinctive muguet-floral cooling aldehyde character

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
288
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Industrial hydroxycitronellal crop production, premium fragrance ingredient supply chain development, clinical TRPM8 aldehyde pharmacology research, and next-generation floral-cooling ingredient programs.

License

$10049 · Tier V License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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