IFI-C · Borneol

Specimen SS-F-CLB-746 // COOL BURN · IFI-C

Borneol IV-AG-B

Lavandula angustifolia

Lavender

Tier IVBorneol

Target Trait

2.74×

fold-change

borneol accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-746

Genomic Edits

7

GC Content

46.7%

Construct Length

3,866 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

TRPM8

IFI Score

274

Pathway Edits

  • BOS (borneol synthase) codon-optimized overexpression for bicyclic terpenoid scaffold
  • GPPS (geranyl pyrophosphate synthase) upregulation for GPP precursor allocation
  • CPR (cytochrome P450 reductase) upregulation for electron transfer to borneol oxidase
  • BD (borneol dehydrogenase) loss-of-function to prevent borneol-to-camphor conversion
  • Borneol glucosyltransferase suppression RNAi to prevent glycoside sequestration

Key Interventions

Borneol bicyclic terpene alcohol overproduction via BOS/GPPS co-upregulation in LavandulaBD suppression to prevent borneol oxidation to camphor and preserve TRPM8-active compoundTRPM8 activation with distinctive camphoraceous-floral cooling character

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
274
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Industrial borneol crop platform, traditional medicine ingredient supply chain modernization, clinical TRPM8 bicyclic agonist research sourcing, and next-generation camphoraceous cooling development.

License

$4049 · Tier IV License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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