IFI-C · Geraniol Balance

Specimen SS-F-CLB-696 // COOL BURN · IFI-C

Geraniol Balance II-IV-B

Lavandula angustifolia

Lavender

Tier IIGeraniol Balance

Target Trait

2.16×

fold-change

geraniol accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-696

Genomic Edits

5

GC Content

47.3%

Construct Length

3,194 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro T7/SP6 cell-free

Host Strain

Cell-free

Receptor Target

TRPM8

IFI Score

216

Pathway Edits

  • GES (geraniol synthase) codon-optimized overexpression cassette in Lavandula angustifolia
  • GPPS (geranyl pyrophosphate synthase) upregulation for GPP precursor flux
  • CYP76C1 (geraniol 10-hydroxylase) loss-of-function to prevent geraniol catabolism
  • GDR (geranyl diphosphate reductase) suppression to prevent competing linalyl pyrophosphate
  • GES2 (geraniol synthase paralogue 2) co-expression for pathway redundancy

Key Interventions

Geraniol TRPM8 agonist overproduction via GES/GES2/GPPS co-upregulation in LavandulaCYP76C1 suppression to prevent geraniol-10-hydroxylase degradation of TRPM8-active compoundFloral cooling TRPM8 activation with characteristic rose-lavender aroma co-production

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
216
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Floral flavor ingredient development, geraniol ingredient sourcing, rose-cooling confectionery formulation, and cosmetic fragrance applications requiring verified TRPM8-active geraniol elevation.

License

$749 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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