IFI-C · Menthyl Acetate

Specimen SS-F-CLB-636 // COOL BURN · IFI-C

Menthyl Acetate V-BL-B

Mentha × piperita

Peppermint

Tier VMenthyl Acetate

Target Trait

4.02×

fold-change

menthyl acetate accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-636

Genomic Edits

8

GC Content

48.7%

Construct Length

4,407 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Receptor Target

TRPM8

IFI Score

402

Pathway Edits

  • BAHD-ATC1 (BAHD acyltransferase 1) codon-optimized overexpression for menthyl ester synthesis
  • AAT2 (alcohol acyltransferase 2) upregulation cassette for ester bond formation
  • PS (pulegone synthase) upregulation for elevated menthol precursor substrate pool
  • Acetyl-CoA supply enhancement cassette for ester substrate availability
  • Menthyl ester hydrolase suppression RNAi to prevent menthyl acetate degradation

Key Interventions

Menthyl acetate ester derivative overproduction via BAHD-ATC1/AAT2 co-upregulationAcetyl-CoA supply engineering for sustained ester biosynthesis substrate provisionTRPM8 activation with distinctive sweet-minty menthyl acetate cooling character

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
402
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Industrial menthyl acetate crop production, next-generation sweet-cooling ingredient supply, clinical TRPM8 ester pharmacology research, and novel fruity-mint flavor platform development.

License

$10049 · Tier V License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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