IFI-C · Menthyl Acetate

Specimen SS-F-CLB-618 // COOL BURN · IFI-C

Menthyl Acetate III-AG-B

Mentha × piperita

Peppermint

Tier IIIMenthyl Acetate

Target Trait

2.82×

fold-change

menthyl acetate accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-618

Genomic Edits

6

GC Content

48.2%

Construct Length

3,679 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

TRPM8

IFI Score

282

Pathway Edits

  • BAHD-ATC1 (BAHD acyltransferase 1) codon-optimized overexpression for menthyl ester synthesis
  • AAT2 (alcohol acyltransferase 2) upregulation cassette for ester bond formation
  • PS (pulegone synthase) upregulation for elevated menthol precursor substrate pool
  • Acetyl-CoA supply enhancement cassette for ester substrate availability
  • Menthyl ester hydrolase suppression RNAi to prevent menthyl acetate degradation

Key Interventions

Menthyl acetate ester derivative overproduction via BAHD-ATC1/AAT2 co-upregulationAcetyl-CoA supply engineering for sustained ester biosynthesis substrate provisionTRPM8 activation with distinctive sweet-minty menthyl acetate cooling character

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
282
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Premium peppermint ester ingredient supply, functional sweet-cooling beverage formulation, pharmaceutical flavoring ingredient development, and unique menthyl ester sensory platform creation.

License

$1549 · Tier III License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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