IFI-C · Linalool Cooling

Specimen SS-F-CLB-367 // COOL BURN · IFI-C

Linalool Cooling I-IV-A

Lavandula angustifolia

Lavender

Tier ILinalool Cooling

Target Trait

1.4×

fold-change

linalool accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-367

Genomic Edits

3

GC Content

44.7%

Construct Length

2,410 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro T7/SP6 cell-free

Host Strain

Cell-free

Receptor Target

TRPM8

IFI Score

140

Pathway Edits

  • LIS (linalool synthase) codon-optimized overexpression cassette in Lavandula angustifolia
  • GPPS (geranyl pyrophosphate synthase) upregulation for GPP precursor flux
  • DXS (1-deoxy-D-xylulose 5-phosphate synthase) MEP pathway rate-limiting step amplification
  • CMK (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) MEP pathway co-upregulation
  • MCT (methylerythritol phosphate cytidylyltransferase) flux enhancement cassette

Key Interventions

Linalool TRPM8 activator overproduction via LIS/GPPS co-upregulation in LavandulaMEP pathway amplification via DXS/CMK/MCT for enhanced linalyl pyrophosphate precursor supplyTRPM8 receptor activation potentiation through elevated linalool tissue concentration

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
140
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Lavender flavor ingredient enhancement, floral cooling formulation, cosmetic fragrance cooling development, and aromatherapy product applications requiring verified linalool elevation.

License

$299 · Tier I License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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