IFI-C · Camphor

Specimen SS-F-CLB-358 // COOL BURN · IFI-C

Camphor V-PR-B

Cinnamomum camphora

Camphor

Tier VCamphor

Target Trait

3.22×

fold-change

camphor accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-358

Genomic Edits

8

GC Content

46.9%

Construct Length

4,281 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Receptor Target

TRPM8

IFI Score

322

Pathway Edits

  • CAM-TS (camphane synthase) codon-optimized overexpression for bicyclic scaffold
  • CPR1 (cytochrome P450 reductase 1) upregulation to support CYP electron transfer
  • CYP71D55 (camphor C-5 exo hydroxylase) precision edit for camphor flux stabilization
  • BOCH (borneol oxidase/camphor hydroxylase) loss-of-function to prevent camphor degradation
  • GPP substrate channeling cassette for monoterpene precursor allocation

Key Interventions

Camphor bicyclic terpenoid overproduction via CAM-TS/CPR1 co-upregulationTRPM8 agonist activation through elevated camphor tissue concentrationBOCH suppression to prevent downstream camphor catabolism and loss

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
322
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Industrial camphor crop engineering, synthetic biology camphor supply chain replacement, clinical TRPM8 research ingredient sourcing, and next-generation bicyclic terpene platform development.

License

$10049 · Tier V License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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