IFI-C · Camphor

Specimen SS-F-CLB-352 // COOL BURN · IFI-C

Camphor IV-IV-B

Cinnamomum camphora

Camphor

Tier IVCamphor

Target Trait

2.7×

fold-change

camphor accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-352

Genomic Edits

7

GC Content

46.2%

Construct Length

3,968 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro T7/SP6 cell-free

Host Strain

Cell-free

Receptor Target

TRPM8

IFI Score

270

Pathway Edits

  • CAM-TS (camphane synthase) codon-optimized overexpression for bicyclic scaffold
  • CPR1 (cytochrome P450 reductase 1) upregulation to support CYP electron transfer
  • CYP71D55 (camphor C-5 exo hydroxylase) precision edit for camphor flux stabilization
  • BOCH (borneol oxidase/camphor hydroxylase) loss-of-function to prevent camphor degradation
  • GPP substrate channeling cassette for monoterpene precursor allocation

Key Interventions

Camphor bicyclic terpenoid overproduction via CAM-TS/CPR1 co-upregulationTRPM8 agonist activation through elevated camphor tissue concentrationBOCH suppression to prevent downstream camphor catabolism and loss

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
270
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Industrial camphor crop engineering, synthetic biology camphor supply chain replacement, clinical TRPM8 research ingredient sourcing, and next-generation bicyclic terpene platform development.

License

$4049 · Tier IV License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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