IFI-C · Camphor

Specimen SS-F-CLB-344 // COOL BURN · IFI-C

Camphor III-IV-B

Cinnamomum camphora

Camphor

Tier IIICamphor

Target Trait

2.18×

fold-change

camphor accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-344

Genomic Edits

6

GC Content

48.9%

Construct Length

3,621 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro T7/SP6 cell-free

Host Strain

Cell-free

Receptor Target

TRPM8

IFI Score

218

Pathway Edits

  • CAM-TS (camphane synthase) codon-optimized overexpression for bicyclic scaffold
  • CPR1 (cytochrome P450 reductase 1) upregulation to support CYP electron transfer
  • CYP71D55 (camphor C-5 exo hydroxylase) precision edit for camphor flux stabilization
  • BOCH (borneol oxidase/camphor hydroxylase) loss-of-function to prevent camphor degradation
  • GPP substrate channeling cassette for monoterpene precursor allocation

Key Interventions

Camphor bicyclic terpenoid overproduction via CAM-TS/CPR1 co-upregulationTRPM8 agonist activation through elevated camphor tissue concentrationBOCH suppression to prevent downstream camphor catabolism and loss

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
218
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Premium camphor oil production, pharmaceutical-grade camphor ingredient supply, cosmetic and personal care cooling ingredient development, and functional food TRPM8 applications.

License

$1549 · Tier III License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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