IFI-C · Eucalyptol

Specimen SS-F-CLB-310 // COOL BURN · IFI-C

Eucalyptol IV-PR-B

Eucalyptus globulus

Eucalyptus

Tier IVEucalyptol

Target Trait

2.93×

fold-change

1,8-cineole accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-310

Genomic Edits

6

GC Content

49.3%

Construct Length

3,674 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Receptor Target

TRPM8

IFI Score

293

Pathway Edits

  • TPS-cin (1,8-cineole terpene synthase) codon-optimized overexpression cassette
  • GPPS2 (geranyl pyrophosphate synthase 2) upregulation for monoterpene precursor flux
  • CYP76F (cytochrome P450 76F subfamily) suppression to reduce competing hydroxylation
  • MCT (methylerythritol phosphate cytidylyltransferase) MEP pathway amplification

Key Interventions

1,8-cineole overproduction via TPS-cin/GPPS2 co-upregulation in Eucalyptus globulusTRPM8 weak-agonist/TRPA1-antagonist dual mechanism via eucalyptol elevationCYP76F suppression to redirect flux toward 1,8-cineole rather than competing oxygenates

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
293
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Industrial eucalyptol ingredient supply chain, clinical respiratory ingredient research, next-generation menthol-alternative platform development, and high-yield eucalyptus crop engineering.

License

$4049 · Tier IV License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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