IFI-C · Eucalyptol

Specimen SS-F-CLB-298 // COOL BURN · IFI-C

Eucalyptol III-AG-B

Eucalyptus globulus

Eucalyptus

Tier IIIEucalyptol

Target Trait

2.42×

fold-change

1,8-cineole accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-298

Genomic Edits

6

GC Content

48.2%

Construct Length

3,639 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

TRPM8

IFI Score

242

Pathway Edits

  • TPS-cin (1,8-cineole terpene synthase) codon-optimized overexpression cassette
  • GPPS2 (geranyl pyrophosphate synthase 2) upregulation for monoterpene precursor flux
  • CYP76F (cytochrome P450 76F subfamily) suppression to reduce competing hydroxylation
  • MCT (methylerythritol phosphate cytidylyltransferase) MEP pathway amplification

Key Interventions

1,8-cineole overproduction via TPS-cin/GPPS2 co-upregulation in Eucalyptus globulusTRPM8 weak-agonist/TRPA1-antagonist dual mechanism via eucalyptol elevationCYP76F suppression to redirect flux toward 1,8-cineole rather than competing oxygenates

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
242
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Premium eucalyptus oil ingredient supply, pharmaceutical-grade 1,8-cineole production, functional food cooling ingredient development, and TRPA1-modulating flavor systems.

License

$1549 · Tier III License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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