IFI-C · Eucalyptol

Specimen SS-F-CLB-296 // COOL BURN · IFI-C

Eucalyptol II-IV-B

Eucalyptus globulus

Eucalyptus

Tier IIEucalyptol

Target Trait

1.9×

fold-change

1,8-cineole accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-296

Genomic Edits

5

GC Content

47.3%

Construct Length

3,194 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro T7/SP6 cell-free

Host Strain

Cell-free

Receptor Target

TRPM8

IFI Score

190

Pathway Edits

  • TPS-cin (1,8-cineole terpene synthase) codon-optimized overexpression cassette
  • GPPS2 (geranyl pyrophosphate synthase 2) upregulation for monoterpene precursor flux
  • CYP76F (cytochrome P450 76F subfamily) suppression to reduce competing hydroxylation
  • MCT (methylerythritol phosphate cytidylyltransferase) MEP pathway amplification

Key Interventions

1,8-cineole overproduction via TPS-cin/GPPS2 co-upregulation in Eucalyptus globulusTRPM8 weak-agonist/TRPA1-antagonist dual mechanism via eucalyptol elevationCYP76F suppression to redirect flux toward 1,8-cineole rather than competing oxygenates

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
190
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Eucalyptus flavor ingredient development, menthol-free cooling formulation, oral care product enhancement, and respiratory wellness product applications.

License

$749 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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