IFI-C · Eucalyptol

Specimen SS-F-CLB-284 // COOL BURN · IFI-C

Eucalyptol I-BL-B

Eucalyptus globulus

Eucalyptus

Tier IEucalyptol

Target Trait

1.38×

fold-change

1,8-cineole accumulation fold-change

Technical Specifications

SKU

SS-F-CLB-284

Genomic Edits

4

GC Content

47.1%

Construct Length

2,779 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Receptor Target

TRPM8

IFI Score

138

Pathway Edits

  • TPS-cin (1,8-cineole terpene synthase) codon-optimized overexpression cassette
  • GPPS2 (geranyl pyrophosphate synthase 2) upregulation for monoterpene precursor flux
  • CYP76F (cytochrome P450 76F subfamily) suppression to reduce competing hydroxylation
  • MCT (methylerythritol phosphate cytidylyltransferase) MEP pathway amplification

Key Interventions

1,8-cineole overproduction via TPS-cin/GPPS2 co-upregulation in Eucalyptus globulusTRPM8 weak-agonist/TRPA1-antagonist dual mechanism via eucalyptol elevationCYP76F suppression to redirect flux toward 1,8-cineole rather than competing oxygenates

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
138
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Eucalyptus flavor ingredient development, menthol-free cooling formulation, oral care product enhancement, and respiratory wellness product applications.

License

$349 · Tier I License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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