IFI-B · Tannic Acid Palatability Series

Specimen SS-F-BTR-693 // ZERO-BITTER · IFI-B

Tannic Acid · T2 Protoplast-A

Vitis vinifera

Grape

Tier IITannic Acid Palatability Series

Target Trait

39%

% reduction

High-MW tannin reduction

Technical Specifications

SKU

SS-F-BTR-693

Genomic Edits

4

GC Content

44.6%

Construct Length

2,763 bp

Promoter System

35S CaMV / RbcS

Expression System

PEG-mediated protoplast transfection

Host Strain

Isolated leaf mesophyll protoplasts

Receptor Target

TAS2R38 (suppression)

IFI Score

39

Pathway Edits

  • ANR anthocyanidin reductase RNAi reduces catechin/epicatechin extension units available for tannin polymerization
  • TT12 tonoplast multidrug transporter RNAi impairs vacuolar sequestration and stabilization of condensed tannins
  • LAR leucoanthocyanidin reductase RNAi reduces (+)-catechin monomer supply for proanthocyanidin polymerization

Key Interventions

ANR RNAi polymerization blockTT12 sequestration silencingLAR monomer suppression

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
39
IFI-K
—
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Tier II Vitis vinifera lines with reduced condensed tannin load for palatable table grape production, low-astringency wine varieties, and grape-derived polyphenol extracts where TAS2R activation is undesirable.

License

$699 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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