Specimen SS-F-AST-984 // ASTRINGENCY · IFI-A
Polyphenol Concentration Scale III-IV-B
Vitis vinifera
Grape
Target Trait
4.6×
fold-change
Total polyphenol broad-spectrum accumulation index
Technical Specifications
SKU
SS-F-AST-984
Genomic Edits
9
GC Content
48.9%
Construct Length
4,641 bp
Promoter System
T7/SP6 cell-free
Expression System
In-vitro cell-free
Host Strain
Cell-free
Receptor Target
Polyphenol-astringency axis
IFI Score
460
Pathway Edits
- MYB14 transcription factor overexpression for stilbene and flavonoid network co-activation
- MYB15 transcription factor amplification for synergistic MYB14 polyphenol network induction
- LAR downstream target activation (leucoanthocyanidin reductase) for PA branch output
- ANR downstream target upregulation (anthocyanidin reductase) for epicatechin PA branch
- TT12 vacuolar transport upregulation for broad-spectrum polyphenol vacuolar sequestration
- TT19 glutathione S-transferase overexpression for PA and flavonoid sequestration efficiency
- AHA10 H+-ATPase activation for vacuolar acidification and polyphenol stability
- Cell-free wheat germ extract reconstitution system
- Enhanced flux via 5'UTR synthetic leader sequence optimization
Key Interventions
IFI Subscale Profile
IFI Profile
Use Case
Commercial total polyphenol concentrate production, mid-range astringency ingredient manufacturing, functional food R&D. Enhanced variant for premium or research-grade applications requiring peak astringency fidelity.
License
$1549 · Tier III License
Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.
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