Sorghum Condensed Tannin Reduction V-AG-A

Sorghum bicolor

Sorghum

Tier VSorghum Condensed Tannin Reduction

Target Trait

75%

% reduction

Condensed tannin anti-nutritional reduction (% reduction from baseline)

Technical Specifications

SKU

SS-F-AST-953

Genomic Edits

GC Content

45.9%

Construct Length

4,016 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

Polyphenol-astringency axis

IFI Score

Pathway Edits

SG4-RNAi silencing (sorghum flavan-4-ol synthase RNAi) for phlobaphene/PA precursor suppression
ANR-RNAi knockdown (anthocyanidin reductase RNAi) for epicatechin extension unit depletion
TT19-RNAi suppression (vacuolar transport RNAi) for PA sequestration efficiency reduction
T-DNA right-border optimized integration cassette

Key Interventions

SG4-RNAi suppression of sorghum flavan-4-ol synthase for phlobaphene PA reductionANR-RNAi depletion of epicatechin extension unit supply for condensed tannin reductionTT19-RNAi vacuolar transport knockdown for PA accumulation limitationAgrobacterium co-cultivation with acetosyringone induction

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

IFI-F

—

Use Case

Flagship industrial sorghum palatability improvement, anti-nutritional tannin reduction at commercial scale, next-generation low-tannin sorghum ingredient manufacturing.

License

$9999 · Tier V License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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