IFI-A · Sorghum Condensed Tannin Reduction
Specimen SS-F-AST-937 // ASTRINGENCY · IFI-A
Sorghum Condensed Tannin Reduction III-AG-A
Sorghum bicolor
Sorghum
Tier IIISorghum Condensed Tannin Reduction
Target Trait
55%
% reduction
Condensed tannin anti-nutritional reduction (% reduction from baseline)
Technical Specifications
SKU
SS-F-AST-937
Genomic Edits
5
GC Content
43.7%
Construct Length
3,122 bp
Promoter System
Tissue-specific 2A11
Expression System
Agrobacterium-mediated T-DNA
Host Strain
EHA105
Receptor Target
Polyphenol-astringency axis
IFI Score
55
Pathway Edits
- SG4-RNAi silencing (sorghum flavan-4-ol synthase RNAi) for phlobaphene/PA precursor suppression
- ANR-RNAi knockdown (anthocyanidin reductase RNAi) for epicatechin extension unit depletion
- TT19-RNAi suppression (vacuolar transport RNAi) for PA sequestration efficiency reduction
- T-DNA right-border optimized integration cassette
Key Interventions
SG4-RNAi suppression of sorghum flavan-4-ol synthase for phlobaphene PA reductionANR-RNAi depletion of epicatechin extension unit supply for condensed tannin reductionTT19-RNAi vacuolar transport knockdown for PA accumulation limitationAgrobacterium co-cultivation with acetosyringone induction
IFI Subscale Profile
IFI Profile
IFI-S—
IFI-U—
IFI-B—
IFI-K—
IFI-C—
IFI-P—
IFI-A55
IFI-F—
Use Case
Commercial low-tannin sorghum ingredient production, mid-range palatability engineering, grain processing R&D.
License
$1499 · Tier III License
Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.
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