IFI-A · Catechin Profile Optimization
Specimen SS-F-AST-353 // ASTRINGENCY · IFI-A
Catechin Profile Optimization V-AG-A
Camellia sinensis
Tea
Tier VCatechin Profile Optimization
Target Trait
3.5×
fold-change
EGCG:ECG:EC catechin molar ratio index
Technical Specifications
SKU
SS-F-AST-353
Genomic Edits
8
GC Content
45.9%
Construct Length
4,396 bp
Promoter System
Tissue-specific 2A11
Expression System
Agrobacterium-mediated T-DNA
Host Strain
EHA105
Receptor Target
Polyphenol-astringency axis
IFI Score
350
Pathway Edits
- ANR differential expression (anthocyanidin reductase) for epicatechin flux control
- LAR allelic balancing (leucoanthocyanidin reductase) for catechin:epicatechin ratio
- F3-5H overexpression (flavonoid 3',5'-hydroxylase) for gallated catechin precursor enrichment
- DFR allelic selection for 3',4'- vs 3',4',5'-dihydroxyl substrate preference
- FLS suppression (flavonol synthase) to redirect dihydroflavonol flux toward catechins
- T-DNA right-border optimized integration cassette
Key Interventions
EGCG:ECG:EC catechin ratio precision control via ANR/LAR differential tuningF3-5H hydroxylation pattern optimization for gallated versus non-gallated catechin distributionDFR allelic switching for substrate specificity toward epicatechin pathwayAgrobacterium co-cultivation with acetosyringone induction
IFI Subscale Profile
IFI Profile
IFI-S—
IFI-U—
IFI-B—
IFI-K—
IFI-C—
IFI-P—
IFI-A350
IFI-F—
Use Case
Flagship premium green tea analog ingredient, pharmaceutical-grade EGCG standardization, precision catechin ratio ingredient production.
License
$9999 · Tier V License
Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.
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